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There are several matches for 'DNA replication initiation factor'.
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1773 matches
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organism
protein
1)
Homo sapiens
MCM10 - Protein MCM10 homolog; Acts as a
replication
initiation
factor
that brings together the MCM2-7 helicase and the
DNA
polymerase alpha/primase complex in order to
initiate
DNA
replication
. Additionally, plays a role in preventing
DNA
damage during
replication
. Key effector of the RBBP6 and ZBTB38-mediated regulation of
DNA
-
replication
and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38. Belongs to the MCM10 family.
[a.k.a. ENSG00000065328, UPI0001B790FF, PRO2249]
2)
Homo sapiens
WDHD1 - WD repeat and HMG-box
DNA
-binding protein 1; Acts as a
replication
initiation
factor
that brings together the MCM2-7 helicase and the
DNA
polymerase alpha/primase complex in order to
initiate
DNA
replication
.
[a.k.a. NM_001008396.2, uc001xbm.3, XP_016876430.1]
3)
Homo sapiens
FAF1 - FAS-associated
factor
1; Ubiquitin-binding protein. Required for the progression of
DNA
replication
forks by targeting
DNA
replication
licensing
factor
CDT1 for degradation. Potentiates but cannot
initiate
FAS-induced apoptosis (By similarity).
[a.k.a. AL603746, FAF1_HUMAN, CCDS554]
4)
Homo sapiens
STN1 - CST complex subunit STN1; Component of the CST complex proposed to act as a specialized
replication
factor
promoting
DNA
replication
under conditions of
replication
stress or natural
replication
barriers such as the telomere duplex. The CST complex binds single-stranded
DNA
with high affinity in a sequence-independent manner, while isolated subunits bind
DNA
with low affinity by themselves.
Initially
the CST complex has been proposed to protect telomeres from
DNA
degradation. However, the CST complex has been shown to be involved in several aspects of telomere
replication
. The CST comp [...]
[a.k.a. ENST00000369764, CCDS7552.1, ENST00000472951.1]
5)
Homo sapiens
TEN1 - CST complex subunit TEN1; Component of the CST complex proposed to act as a specialized
replication
factor
promoting
DNA
replication
under conditions of
replication
stress or natural
replication
barriers such as the telomere duplex. The CST complex binds single-stranded
DNA
with high affinity in a sequence-independent manner, while isolated subunits bind
DNA
with low affinity by themselves.
Initially
the CST complex has been proposed to protect telomeres from
DNA
degradation. However, the CST complex has been shown to be involved in several aspects of telomere
replication
. The CST comp [...]
[a.k.a. CST complex subunit TEN1, ENSG00000257949, chromosome 17 open reading frame 106]
6)
Homo sapiens
CTC1 - CST complex subunit CTC1; Component of the CST complex proposed to act as a specialized
replication
factor
promoting
DNA
replication
under conditions of
replication
stress or natural
replication
barriers such as the telomere duplex. The CST complex binds single-stranded
DNA
with high affinity in a sequence-independent manner, while isolated subunits bind
DNA
with low affinity by themselves.
Initially
the CST complex has been proposed to protect telomeres from
DNA
degradation. However, the CST complex has been shown to be involved in several aspects of telomere
replication
. The CST comp [...]
[a.k.a. CTC1-214, URS0000D6E982, XR_001752643.1]
7)
Homo sapiens
MCM5 -
DNA
replication
licensing
factor
MCM5; Acts as component of the MCM2-7 complex (MCM complex) which is the putative
replicative
helicase essential for 'once per cell cycle'
DNA
replication
initiation
and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
[a.k.a. R-HSA-69278, R-HSA-69620, MCM5-204]
8)
Homo sapiens
MCM4 -
DNA
replication
licensing
factor
MCM4; Acts as component of the MCM2-7 complex (MCM complex) which is the putative
replicative
helicase essential for 'once per cell cycle'
DNA
replication
initiation
and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
[a.k.a. ENST00000520637, ENST00000648519.1, ENST00000518680.1]
9)
Homo sapiens
MCM6 -
DNA
replication
licensing
factor
MCM6; Acts as component of the MCM2-7 complex (MCM complex) which is the putative
replicative
helicase essential for 'once per cell cycle'
DNA
replication
initiation
and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
[a.k.a. ENST00000456117, MCM6-203, R-HSA-69278]
10)
Homo sapiens
MCM2 -
DNA
replication
licensing
factor
MCM2; Acts as component of the MCM2-7 complex (MCM complex) which is the putative
replicative
helicase essential for 'once per cell cycle'
DNA
replication
initiation
and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
[a.k.a. ENSP00000321118, CDCL1, 4171]
11)
Homo sapiens
MCM7 -
DNA
replication
licensing
factor
MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative
replicative
helicase essential for 'once per cell cycle'
DNA
replication
initiation
and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
[a.k.a. ENST00000343023.10, ENST00000325313, R-HSA-69278]
12)
Homo sapiens
MCM3 -
DNA
replication
licensing
factor
MCM3; Acts as component of the MCM2-7 complex (MCM complex) which is the putative
replicative
helicase essential for 'once per cell cycle'
DNA
replication
initiation
and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
[a.k.a. UPI0002065906, P25205, OMIM:602693]
13)
Mus musculus
Mcm10 - Protein MCM10 homolog; Acts as a
replication
initiation
factor
that brings together the MCM2-7 helicase and the
DNA
polymerase alpha/primase complex in order to
initiate
DNA
replication
. Additionally, plays a role in preventing
DNA
damage during
replication
. Key effector of the RBBP6 and ZBTB38-mediated regulation of
DNA
-
replication
and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38 (By similarity).
[a.k.a. R-MMU-453279, ENSMUST00000125851.1, R-MMU-69306]
14)
Mus musculus
Wdhd1 - WD repeat and HMG-box
DNA
-binding protein 1; Acts as a
replication
initiation
factor
that brings together the MCM2-7 helicase and the
DNA
polymerase alpha/primase complex in order to
initiate
DNA
replication
.
[a.k.a. P59328, A0A2I3BQ38, mmu:218973]
15)
Mus musculus
Ten1 - CST complex subunit TEN1; Component of the CST complex proposed to act as a specialized
replication
factor
promoting
DNA
replication
under conditions of
replication
stress or natural
replication
barriers such as the telomere duplex. The CST complex binds single-stranded
DNA
with high affinity in a sequence-independent manner, while isolated subunits bind
DNA
with low affinity by themselves.
Initially
the CST complex has been proposed to protect telomeres from
DNA
degradation. However, the CST complex has been shown to be involved in several aspects of telomere
replication
. The CST comp [...]
[a.k.a. CST complex subunit TEN1, ENSMUSP00000021130, TEN1 telomerase capping complex subunit]
16)
Mus musculus
Stn1 - CST complex subunit STN1; Component of the CST complex proposed to act as a specialized
replication
factor
promoting
DNA
replication
under conditions of
replication
stress or natural
replication
barriers such as the telomere duplex. The CST complex binds single-stranded
DNA
with high affinity in a sequence-independent manner, while isolated subunits bind
DNA
with low affinity by themselves.
Initially
the CST complex has been proposed to protect telomeres from
DNA
degradation. However, the CST complex has been shown to be involved in several aspects of telomere
replication
. The CST comp [...]
[a.k.a. Stn1-202, ENSMUST00000182873.1, Stn1-207]
17)
Mus musculus
Ctc1 - CST complex subunit CTC1; Component of the CST complex proposed to act as a specialized
replication
factor
promoting
DNA
replication
under conditions of
replication
stress or natural
replication
barriers such as the telomere duplex. The CST complex binds single-stranded
DNA
with high affinity in a sequence-independent manner, while isolated subunits bind
DNA
with low affinity by themselves.
Initially
the CST complex has been proposed to protect telomeres from
DNA
degradation. However, the CST complex has been shown to be involved in several aspects of telomere
replication
. The CST comp [...]
[a.k.a. Ctc1-208, ENSMUST00000021278.13, ENSMUST00000161271.1]
18)
Mus musculus
Faf1 - FAS-associated
factor
1; Ubiquitin-binding protein (By similarity). Required for the progression of
DNA
replication
forks by targeting
DNA
replication
licensing
factor
CDT1 for degradation (By similarity). Potentiates but cannot
initiate
FAS-induced apoptosis.
[a.k.a. uc008uct.1, FAF1_MOUSE, Dffrx]
19)
Mus musculus
Mcm7 -
DNA
replication
licensing
factor
MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative
replicative
helicase essential for 'once per cell cycle'
DNA
replication
initiation
and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
[a.k.a. R-MMU-453279, R-MMU-69306, ENSMUST00000148094.7]
20)
Mus musculus
Mcm4 -
DNA
replication
licensing
factor
MCM4; Acts as component of the MCM2-7 complex (MCM complex) which is the putative
replicative
helicase essential for 'once per cell cycle'
DNA
replication
initiation
and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
[a.k.a. R-MMU-453279, MCM4_MOUSE, R-MMU-69306]
1773 matches
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